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Prolotherapy for chronic pain - newest research and physician resoures.

Standard Clinical X-ray Studies Document Cartilage Regeneration
JP is a 60 year-old female who was first seen in October 2005 complaining of a three year history of bilateral knee pain (see Prolotherapy research paper). She rated her right knee pain as 6 and her left knee as a 5 on the VAS. The pain in both knees occurred primarily in the medial area. Rising from a chair, taking the stairs, and simply walking caused pain.

The Case for Utilizing Prolotherapy as First-Line Treatment for Meniscal Pathology: A Retrospective Study Shows Prolotherapy is Effective in the Treatment of MRI-Documented Meniscal Tears and Degeneration
Ross A. Hauser, MD, Hilary J. Phillips, and Havil S. Maddela

ABSTRACT
Meniscus injuries are a common cause of knee pain, accounting for one sixth of knee surgeries. Tears are the most common form of meniscal injuries, and have poor healing ability primarily because less than 25% of the menisci receive a direct blood supply. While surgical treatments have ranged from total to partial meniscectomy, meniscal repair and even meniscus transplantation, all have a high long-term failure rate with the recurrence of symptoms including pain, instability, locking, and re-injury. The most serious of the longterm consequences is an acceleration of joint degeneration. This poor healing potential of meniscus tears and degeneration has led to the investigation of methods to stimulate biological meniscal repair.

Read Prolotherapy and Meniscal Injury Research

Cartilage Regeneration in Five Degenerated Knees
After Prolotherapy


ABSTRACT
Degenerative Joint Disease is the most common form of arthritis. The condition is marked by progressive destruction of the articular cartilage which is easily documented by standard X-ray studies. The regeneration of this articular cartilage in clinical practice has been difficult. Five knees with articular cartilage degeneration were treated with Prolotherapy in this report. Each of the five knees showed improvement of their standard clinical X-rays after the Prolotherapy, signifying articular cartilage repair with Prolotherapy. It is suggested that before and after X-ray studies can be used to document the response of degenerated joints to Prolotherapy.

Read Cartilage Regeneration in Five Degenerated Knees After Prolotherapy

Prolotherapy and Knee Pain
The Prolotherapy and knee pain page contains articles on Knee Replacement and Prolotherapy, Pes Anserinus Tendon, ACL Surgery and other problems, the Patella, surgically failed knee, Bilateral Knee Replacements

Watch Prolotherapy to the Knee Videos

A Retrospective Study on Hackett-Hemwall Dextrose Prolotherapy for Chronic Hip Pain at an Outpatient Charity Clinic in Rural Illinois
Design: Sixty-one patients, representing 94 hips who had been in pain an average of 63 months, were treated quarterly with Hackett-Hemwall dextrose Prolotherapy. This included a subset of 20 patients who were told by their medical doctor(s) that there were no other treatment options for their pain and a subset of eight patients who were told by their doctor(s) that surgery was their only option. Patients were contacted an average of 19 months following their last Prolotherapy session and asked questions regarding their levels of pain, physical and psychological symptoms and activities of daily living, before and after their last Prolotherapy treatment.

Results: In these 94 hips, pain levels decreased from 7.0 to 2.4 after Prolotherapy; 89% experienced more than 50% of pain relief with Prolotherapy; more than 84% showed improvements in walking and exercise ability, anxiety, depression and overall disability; 54% were able to completely stop taking pain medications. The decrease in pain reached statistical significance at the p<.0001 for the 94 hips, including the subset of patients who were told there was no other treatment options for their pain and those who were told surgery was their only treatment option.

Conclusion: In this retrospective study on the use of Hackett-Hemwall dextrose Prolotherapy, patients who presented with over five years of unresolved hip pain were shown to improve their pain, stiffness, range of motion, and quality of life measures even 19 months subsequent to their last Prolotherapy session. This pilot study shows that Prolotherapy is a treatment that should be considered and further studied for people suffering with unresolved hip pain.
Read entire hip research paper



More articles on hip pain
Biological Reconstruction - Alternatives to Hip Prosthesis William J. Faber, D.O.

Prolotherapy, Hip Pain & Snapping Hip Syndrome Ross Hauser, M.D.

Hip Pain and Prolotherapy Ross Hauser, M.D.

Prolotherapy for Pelvic Ligament Pain:
A Case Report
This case study examines the effect of the addition of Prolotherapy to manual therapy, and pelvic and trunk exercises, in a treatment regime for a patient with pelvic and chronic low back pain (CLBP) who had previously failed manual therapy and exercise alone and in combination. We hypothesized that with continued exercise and the combination of Prolotherapy and manual therapy, there would be better improvement than any single intervention to reduce pain and improve stability in the lumbar spine and pelvis. Read Prolotherapy for Pelvic Ligament Pain: A Case Report

Prolotherapy Helps Patient with Spinal Cord Compression
Mr. K is a 35 year-old office clerk. He has a long history of neck and shoulder pain due to prolonged usage of a computer with a forward-head posture. He injured his neck one day when he was playing with his son in a playground. While supporting his body weight hanging from a play set, he tried to move forward using both hands from one bar to another. He suddenly felt a severe pain in his neck and both hands which caused him to fall down to the ground. He had weakness in all four limbs initially making weight bearing impossible. He gradually regained full walking ability 15 minutes later. His neck pain has continued and he has not been able to make firm grips with both hands since the injury.

The Theoretical Basis for and Treatment of
Complex Regional Pain Syndrome with Prolotherapy
Complex regional pain syndrome (CRPS) typically refers to post-traumatic pain that spreads from the site of injury, exceeds in magnitude and duration the expected clinical course of the inciting event, and progresses variably over time. Burning pain is the primary symptom, but patients frequently report allodynia, changes in the color or temperature of the skin, and if the condition progresses, trophic changes of the skin, nails, and bone occur. The condition produces a high degree of suffering, lost productivity and cost of treatment. While there are many theories as to why CRPS occurs, success in treatment of CRPS with traditional medical therapies is dismal.

20-Year History of Chronic Body Pain
Cured with Prolotherapy
This article discusses the case of 57 year-old Bill B, a dentist, who suffered from chronic pain from ligamentous laxity and degenerative disc disease in the cervical, lumbar and thoracic spine. His headaches and back pain were treated successfully with Prolotherapy even after many years of other treatments with failed results. Read article

A Case History - Headache, Jaw and Neck Pain
Ms. A is a 30 year-old financial planner, with a five year history of headaches, vertigo, tinnitus, ear pain, jaw pain, pain on wide-opening of mouth, and neck pain. She also describes a pins-and-needles sensation of the hands and forearms during sleep or prolonged use of a computer. She has difficulty concentrating on her work when she has the attacks. She had seen a lot of doctors for help. Her cervical MRIs were unremarkable.
Headache, Jaw and Neck Pain

Dextrose Prolotherapy For Unresolved Neck Pain
An observational study of patients with unresolved neck pain who were treated with dextrose Prolotherapy at an outpatient charity clinic in rural Illinois. Conclusion: In this observational study, patients with unresolved neck pain reported clinically relevant improvements in their pain level and quality of life after receiving Hemwall-Hackett dextrose Prolotherapy.

Cervical Radiculopathy Improves with Prolotherapy
A 38 year-old male, came in April 2008 with complaints of severe pain in his neck that radiated down his right arm with numbness of his right index finger and posterior wrist (C6 distribution). His pain began earlier that month after lifting a TV. Prior to this injury he was an active person who did not have pain. He stated that his pain was at its worst when lying down (a 10 out of 10 pain), but is helped by wearing a neck brace while sleeping. He was taking Norco two to three times per day for pain, a Medrol dose pack, and Daypro at the time of his first visit. An MRI ordered by his primary doctor revealed a right sided disc herniation at C5-C6 and C6-C7.

Prolotherapy: A Literature Review and Retrospective Study
Abstract. Proliferative therapy (prolotherapy) is the process whereby dextrose, P25G or sodium morrhuate is injected into ligaments in order to produce a proliferating response of that ligament. The purpose of these injections is to strengthen ligamentous structures and relieve pain. A review of the literature is provided and a retrospective study presented which demonstrates a 66% redction of sacroiliac low back pain in two-thirds of the patients who received this form of treatment. Robert G. Schwartz, M.D. and Noreen Sagedy, M.D., Prolotherapy: A Literature Review and Retrospective Study The Journal of Neurological and Orthopedic Medicine and Surgery, Vol. 12. No. 3. 1991.

Introduction to Prolotherapy Links

What is Prolotherapy-Indications and Contraindications
K. Dean Reeves, M.D.
Prolotherapy is injection of any substance that acts as a ‘growth factor,’ that is, which promotes growth of normal cells, tissues, or organs. Injection of the hormone, erythropoietin, to produce red blood cells is widely used, and a number of other substances have been used for treatment of patients with various medical disorders. This discussion focuses on prolotherapy for musculoskeletal disorders, including arthritis and back pain. 

Why Get Prolotherapy?
Donna Alderman, D.O.
When you become a physician, you take the Hippocratic Oath. The first rule of the Hippocratic Oath is "First of all, do no harm." This is why Prolotherapy appealed to me as a physician. I was a doctor at a famous HMO. After learning Prolotherapy, however, I went into private practice.

What is Prolotherapy?
Alvin Stein, M.D.
Prolotherapy is also known as non-surgical ligament reconstruction, and is a permanent treatment for chronic pain. Prolotherapy is derived from the Latin word "proli" which means to regenerate or rebuild. It is important to understand what the word PROLOTHERAPY itself means. "Prolo" is short for proliferation, because the treatment causes the proliferation (growth, formation) of new ligament tissue in areas where it has become weak.

10 Tips to Determine if You Are A Good Prolotherapy Candidate
Ross Hauser, M.D.
Pain simply put is just the body’s response telling you that you have some tissue that is breaking down. The same thing happens to an athlete who is in the heat of competition. When the muscles start hurting, it is just a sign that you are working really hard. It also reveals that tissue is breaking down, which is especially important to those who are athletes. The goal of Prolotherapy is to build the tissue back up.

Non-Surgical Tendon, Ligament and Joint Reconstruction
William J. Faber, D.O.
In acute injuries, the ligaments and tendons become torn. Ligaments function to limit the range of motion that bones can move between each other, and function to stabilize joints and hold the joint together. Tendons function to attach a muscle to bone in order to provide motion. Discs and cartilage serve to absorb shock and keep the bones from rubbing against one another. If the ligaments become torn or over-stretched the joint becomes unstable and resultant friction causes the discs or cartilage to become worn down causing a loss of height.

How Does Prolotherapy Work?
Marc Darrow, M.D.
The term "Prolotherapy" is short for "proliferation therapy." Proliferation, of course, means "rapid production." What Prolotherapy rapidly produces is collagen and cartilage. Collagen is a naturally occurring protein in the body that is a necessary element for the formation of new connective tissue—the tissues that holds our skeletal infrastructure together. These tissues include, tendons, ligaments, muscle fascia and joint capsular tissue.

Read more articles including

Prolotherapy and Back Pain

Prolotherapy and Spine Disorders
Jay W. Nielsen, M.D.

Prolotherapy after Back Surgery
Prolotherapy and Scoliosis
Failed Back Surgery and Prolotherapy
Low Back Pain and Prolotherapy
DEGENERATIVE DISC DISEASE
Ross Hauser, M.D.

Identifying Different Types of Back Pain
Marc Darrow, M.D.

Spinal Cord Stimulator
Ross Hauser, M.D.

Sciatica
Marc Darrow, M.D.

Prolotherapy and Disc Problems
Richard I. Gracer, M.D.

Complicated Disc Problem
Marc Darrow, M.D.

Herniated Discs
Sacroiliac pain

Prolotherapy: An Alternative
to Thoracic Spine Surgery
Ross Hauser, M.D.

Spinal Fusion Questions

Low Back Pain Resolved With Prolotherapy
Spinal Disc Problems
Ross Hauser, M.D

Prolotherapy and Shoulder Pain
The Prolotherapy and shoulder pain with articles on rotator cuff tendonitis, rotator cuff tear degenerative joint disease, joint replacements Meniscal Injury, advanced Osteoarthritis, labral tears of the shoulder, SLAP lesion.

Watch Prolotherapy to the Shoulder Videos

Prolotherapy, Foot and Ankle Pain and Hip Pain

Prolotherapy and Ankle Pain
CASE HISTORIES PROLOTHERAPY
AND ANKLE PAIN

ANKLE FUSION AND PROLOTHERAPY
Ross Hauser, M.D.

The Key to Treatment of Any Joint Pain Lies in the Foot
Scott Greenberg, M.D.

Prolotherapy and Foot Pain
Foot Pain and Prolotherapy
Ross Hauser, M.D.

Covering Tarsal Tunnel Syndrome and Morton's Neuroma
Ross Hauser, M.D.

Chronic Foot Problems
Ross Hauser, M.D.

When Prolotherapy is Not Working

When Prolotherapy is Not Working
(Multiple Articles)

Don't Prevent Prolotherapy From Working!
Marc Darrow, M.D.J.D.

What Is The Proof Prolotherapy Is Working?
Ross Hauser, M.D.

How to Optimize Response To Prolotherapy
Ross Hauser, M.D.

Other Articles

Prolotherapy and Chronic Body Pain
Benign congenital hypermobility (BCH)
Benign Congenital Hypermobility (BCH) is generalized joint hypermobility (loose joints in the entire body) due to ligamentous laxity occurs in about five percent of the population. This may be a genetic problem.

Affecting individuals over 40 years of age, typically these people have recurrent joint problems and almost universally suffer from chronic pain. The end result of this condition is often diffuse osteoarthritis.
Ross Hauser, M.D.

Prolotherapy and Collagen
Rebuilding Collagen: The Key to Prolotherapy
Marc Darrow, M.D.

Prolotherapy and Elbow Pain
ulnar collateral ligament sprain
Elbow Pain
Elbow Pain ulnar collateral ligament
A common cause of chronic elbow pain is an ulnar collateral ligament sprain. This ligament supports the inside of the elbow. It is responsible for holding the ulnar bone to the distal end of the humerus. In other words it enables the arm to flex, pivoting at the elbow. A patient's complaint of pain on the inside of the elbow will cause a physician to examine the lateral epicondyle's "sister," the medial epicondyle and not look for the ulnar collateral ligament (UCL) sprain. Ross Hauser, M.D.

Prolotherapy and Sports Injuries
Prolotherapy and Sports Injuries
Ross Hauser, M.D.

Resolve Joint Pain Without Surgery
William J. Faber, D.O.

CASE HISTORIES FOR PROLOTHERAPY
& SPORTS INJURIES 

Prolotherapy and TMJ
Ross Hauser, M.D.

BARRE-LIEOU SYNDROME AND TMJ
Marc Darrow, M.D.

Prolotherapy and Ligament Injury
The 7 No's of Ligament Injury
Ross Hauser, M.D.
Prolotherapy and Ligament Pain
Robert G. Schwartz MD

Prolotherapy and Head/Neck Pain
Nerve Pain in the Neck and Shoulder Area
Marc Darrow, M.D.

The Diagnostic Evaluation of Referred Jaw Temporal and Facial Pain
Scott R. Greenberg, M.D.

Other articles
Prolotherapy articles
Prolotherapy.org
Newsletter articles

Case Histories
Golf, Diet and Prolotherapy
Woman Mid 60's - knee pain
Prolotherapy & other ways to get pain-free

Prolotherapy and Arthritis
Prolotherapy Can Prevent the Development of Traumatic Arthritis
Ligaments stabilize joints, if ligaments are loose, the joint is loose. Loose joints means the body will cause muscles to spasm and overgrow bone in an effort to stabilize the joint. Since stabilization will not occur; the joint will begin to make the "cracking" sound. Cracking of a joint means arthritis is starting. Additionally, if the joint periodically swells or feels painful during cold weather, arthritis is starting to form. If a joint or ligament is traumatized by injury and not fully allowed to heal, traumatic arthritis develops. Many of the old-time athletes I see in my practice have some form of traumatic arthritis. However! Exercise and sports participation do not cause arthritis; only an injury to the joint causes arthritis.
Donna Alderman, D.O.

Prolotherapy: An Alternative to Arthritis Surgery
People are often getting surgery for degenerative conditions. The most common surgery is arthroscopy which was found to be no more effective than placebo in regard to knee arthritis. There are still hundreds of thousands of joint replacements every year for degenerative joint disease. There are hundreds of thousands of more surgeries for degenerative disc disease. Let's see if surgery makes sense for these conditions.
Ross Hauser, M.D.

Arthritis
Like all types of joint pain, knee pain and back pain can appear either suddenly, as with an acute injury which may be a result of a sports injury or trauma, or be chronic (long lasting) often as a result of overuse of some sort. The most common cause of chronic knee and back pain and disability is Osteoarthritis, although other forms of arthritis can be culprits as well, including Rheumatoid Arthritis, traumatic arthritis, and gouty arthritis.
Ross Hauser, M.D.

Prolotherapy and Groin Pain
Groin Pain Blog

Prolotherapy and Headache (Migraines)
Prolotherapy & Barre-Lieou Syndrome
Ross Hauser, M.D.

Prolotherapy and Inflammation
Prolotherapy: Creating Inflammation
Can I Take Anti-Inflammatory Agents?
Diet and Inflammation
Creating Inflammation with Prolotherapy

Prolotherapy and Pain Killers
Can I Take Anti-Inflammatory Agents With Prolotherapy? Ross Hauser, M.D.

Prolotherapy and Platlet Rich Plasma
Prolotherapy with Platelet Rich Plasma

Prolotherapy and Whiplash Injuries
Prolotherapy for Whiplash, Chronic Neck Pain and Headaches Vladimir Djuric, M.D.

Whiplash Injury
Myofasciitis
Marc Darrow, M.D.

Prolotherapy for Post-Fracture
Rehab and Pain
Ross Hauser, M.D.

 

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